This work advances the understanding of the production and purpose of the Ps.-Oecumenian catena on Ephesians through the creation of a critical edition, its translation, and theological commentary. The edition is created through the full transcription and collation of seventeen catena manuscripts, drawn from all known catena manuscripts containing the Ps.-Oecumenian catena on Ephesians. The selected manuscripts were chosen on the basis of a test passage applied to all manuscript witnesses of this catenae tradition and they represent three of the main catena types established by Karl Staab and indicative of the development of the catena from its earliest recoverable period containing the  Urkatena  and Corpus Extravagantium , to the addition of the Scholia Photiana . An analysis of the seventeen manuscripts selected for the edition is provided alongside a stemma codicum representing a conceptualisation of textual relationships between the manuscripts and the process of the transmission of the catena. The presence of author attributions in the manuscript tradition and the source material of unattributed scholia are examined with discussions related to their reliability. The identification of Oecumenius as a source for select scholia within the catena is paralleled with similar material in the commentary on the Apocalypse produced by Oecumenius, concluding that the same source is likely responsible for both. The editorial text of the critical edition is presented alongside its English translation with an accompanying theological commentary. The commentary analyses the content of each scholion in light of patristic exegesis from the second to seventh centuries. A critical edition with apparatus is provided for the entire catena of Ephesians with a separate edition and apparatus, with English translation, included for the  Scholia Photiana .