Part 1 Clinical reasoning.- 1. Background knowledge.- 2. Decision on diagnosis: what is the problem?.- 3. Decision on etiology: what caused the problem?.- 4. Decision on prognosis: what can be achieved?.- 5. Decision on therapy: what can we do about the problem?.- Part 2 Evidence-based practice.- 6. Clinical reasoning and evidence-based practice.- 7. What is the problem: how to appraise scientific articles on diagnostic tests?.- 8. What caused the problem: how to appraise scientific articles on etiological factors?.- 9. What can be achieved: how to appraise scientific articles on prognostic research?.- 10. What can we do about the problem: how to appraise scientific articles on interventions?.- 11. How to reach a better understanding of the patients' perspective: reading and appraising qualitative research.- Part 3 Extra's.- Chapter 12. Deepen your knowledge.- Chapter 13. Education about clinical reasoning and evidence-based practice.