Just as Nyla Rowe's FBI task force is coming closer to identifying the elusive leaders of the Proteus Group, their luck changes. The Creators Almighty has been instrumental in tracking Dark Web activities that have helped capture a number of cells, but now they are under attack. Though determined to continue with her mission, Sage Lomax's health is failing and her high-tech prescience is becoming dangerously unreliable. While Frank Gillett searches for Weinberg's dispersed Isabellas, who are all suddenly becoming pregnant with only daughters, the Proteus Group prepares to counter the worldwide threats facing it by launching Operation Strikeback.