Since its founding in 1943, Medievalia et Humanistica has won worldwide recognition as the first scholarly publication in America to devote itself entirely to medieval and Renaissance studies. Since 1970, a new series, sponsored by the Modern Language Association of America and edited by an international board of distinguished scholars and critics, has published interdisciplinary articles. In yearly hardcover volumes, the new series publishes significant scholarship, criticism, and reviews treating all facets of medieval and Renaissance culture: history, art, literature, music, science, law, economics, and philosophy. Volume 48 is a special issue that presents the outcome of an international workshop ("Transnational Aspects of Early Modern Drama") held (virtually) at Ruhr-Universität Bochum in June 2021. The conference was hosted by Jan Bloemendal, one of the most distinguished scholars in the field. This volume contains six transnational and/or translingual case studies of early modern theatre and four reviews which cover various epochs, genres and discourses.