This book presents the latest research advances relating to machines and mechanisms. Featuring papers from the XIII International Conference on the Theory of Machines and Mechanisms (TMM 2020), held in Liberec, Czech Republic, on September 7-9, 2021, it includes a selection of the most important new results and developments. The book is divided into five parts, representing a well-balanced overview, and spanning the general theory of machines and mechanisms, through analysis and synthesis of planar and spatial mechanisms, linkages and cams, robots and manipulators, dynamics of machines and mechanisms, rotor dynamics, computational mechanics, vibration and noise in machines, optimization of mechanisms and machines, mechanisms of textile machines, mechatronics and control and monitoring systems of machines. This conference is traditionally held every four years under the auspices of the international organisation IFToMM and the Czech Society for Mechanics.