An archeological team discovered a mysterious relic clutched in the skeletal hands of an old woman at the floor of the Mediterranean Sea. The ship never makes it to shore. Years later, two children are abducted from their bedrooms on opposite sides of Washington DC, a note left behind details the torture of their abductor and invites the FBI into a game for their safe return. This note leads the investigators to two serial killers, one incarcerated and one not, a terrifying, millennia-old mystery that has come to the surface, and a woman, shrouded in evil, that has become the mastermind of all their worst nightmares.